In 1796 British doctor Edward Jenner demonstrated how infection from cowpox gave rise to immunity from smallpox. This led to the first vaccination in history and represented the first step in the total eradication of smallpox, the only human disease to ever be totally globally eradicated. Edward Jenner | Illustrated London News | 27 January 1923 With vaccination again hitting the headlines during the COVID-19 pandemic, we set out to discover how Edward Jenner’s contemporaries reacted to his groundbreaking vaccination method, and …